Description
Description
Bordetella pertussis ImmuneSelect peptide pool is composed of 46 peptides derived from the following proteins:
- Pertussis toxin subunit 1 (UniProt:P04977)
- Pertactin autotransporter (UniProt:P14283)
- Filamentous hemagglutinin (UniProt:P12255)
- Membrane protein insertase YidC (UniProt:P65622)
- Pertussis toxin subunit 2 (UniProt:P04978)
The peptides include both MHC-I and MHC-II epitopes and the purity of each peptide is ≥90% (HPLC-MS).
Application
The in-vitro stimulation of Peripheral Blood Mononuclear Cells (PBMCs) with B. pertussis ImmuneSelect Peptide Pool activates memory T cells specific to the virus, leading to cytokine secretion and the increased expression of specific surface markers.
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