EBV ImmuneSelect Peptide Pool Premium

£195.00

The Epstein-Barr virus (EBV), also known as human herpesvirus 4 (HHV-4), formally called Human gammaherpesvirus 4, is one of the nine known human herpesvirus types. EBV has two major types: EBV type 1 (EBV-1) and EBV type 2 (EBV-2). EBV-type 1 is the most common type of EBV worldwide; EBV-type 2 accounts for a smaller proportion of EBV infections in humans.

The EBV peptide pool contains 44 peptides (8-21mer) from Human herpesvirus 4 (Epstein Barr virus), MHC class–I & II. Peptide sequences as T cell epitopes are collected from the Glycoprotein, EBNA-3A and 3B, membrane protein, BARF1 protein, LMP1 protein and others.

The purity of each peptide is ≥90% (HPLC-MS).

Category:

Description

Description

The EBV peptide pool contains 44 peptides (8-21mer) from Human herpesvirus 4 (Epstein Barr virus), derived from the following protein

  • BARF1 protein
  • BZLF1
  • DNA polymerase catalytic subunit
  • EBNA-1 (Epstein-Barr nuclear antigen 1)
  • EBNA-2
  • EBNA-3A
  • EBNA-3B
  • EBNA-6
  • Glycoprotein GP110 precursor (MTP, p140)
  • Large tegument protein deneddylase
  • LMP1 (Latent membrane protein 1)
  • LMP2A/B
  • Envelope membrane glycoprotein GP350
  • Transcription activator BRLF1

 

The peptide sequences are a mixture of MHC class–I & MHC class–II epitopes.  The purity of each peptide is ≥90% (HPLC-MS).

 

Application

The in-vitro stimulation of Peripheral Blood Mononuclear Cells (PBMCs) with EBV ImmuneSelect Peptide Pool activates memory T cells specific to the virus, leading to cytokine secretion and the increased expression of specific surface markers.

Reviews

There are no reviews yet.

Be the first to review “EBV ImmuneSelect Peptide Pool Premium”

Your email address will not be published. Required fields are marked *

Related products