Description
Description
Herpes Simplex Virus 2 (HSV-2) ImmuneSelect peptide pool is composed of 45 peptides derived from the following proteins:
- Envelope glycoprotein D (UniProt:Q69467)
- E3 ubiquitin-protein ligase ICP0 (UniProt:P28284)
- Tegument protein VP16 (UniProt:P68336)
- Tegument protein VP22 (UniProt:P89468)
The peptides include both MHC-I and MHC-II epitopes and the purity of each peptide is ≥90% (HPLC-MS).
Application
The in vitro stimulation of Peripheral Blood Mononuclear Cells (PBMCs) with HSV-2 ImmuneSelect Peptide Pool activates memory T cells specific to the virus, leading to cytokine secretion and the increased expression of specific surface markers.
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