Description
Description
Human papillomavirus 16 (HPV-16) ImmuneSelect peptide pool is composed of 45 peptides derived from the following proteins:
- Protein E7 (UniProt:P03129)
- Protein E6 (UniProt:P03126)
- Regulatory protein E2 (UniProt:P03120)
- Replication protein E1 (UniProt:P03114)
- Major capsid protein L1 (UniProt:P03101)
The peptides include both MHC-I and MHC-II epitopes and the purity of each peptide is ≥90% (HPLC-MS).
Application
The in vitro stimulation of Peripheral Blood Mononuclear Cells (PBMCs) with HPV-16 ImmuneSelect Peptide Pool activates memory T cells specific to the virus, leading to cytokine secretion and the increased expression of specific surface markers.
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