Description
Description
Varicella zoster virus (VZV) ImmuneSelect peptide pool is composed of 46 peptides derived from the following proteins:
- Envelope glycoprotein E (UniProt:P09259)
- mRNA export factor ICP27 homolog (UniProt:P09269)
- Transcriptional regulator ICP22 homolog (UniProt:P09255)
- Tegument protein VP22 (UniProt:P09272)
- Envelope glycoprotein H (UniProt:P09260)
- Tegument protein UL46 homolog (UniProt:P09264)
The peptides include both MHC-II epitopes and the purity of each peptide is ≥90% (HPLC-MS).
Application
The in vitro stimulation of Peripheral Blood Mononuclear Cells (PBMCs) with VZV ImmuneSelect Peptide Pool activates memory T cells specific to the virus, leading to cytokine secretion and the increased expression of specific surface markers.
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